The lab of Dr. Bruce Walcheck (walchecklab.umn.edu) seeks a highly motivated individual for an NIH-funded postdoctoral position at the University of Minnesota (twin-cities.umn.edu).
Our
research is focused on the cell and molecular biology of leukocytes in
the context of inflammation and the host response to cancer. Ectodomain
shedding by specific membrane-associated proteases occurs in the
microenvironment of the cell membrane of leukocytes and regulates the
surface density of various receptors and the release of cell stimulatory
factors. This process is central to the regulation of assorted
leukocyte effector functions, such as neutrophil recruitment at sites of
infection as well as controlling the expression levels of particular
activating receptors on natural killer (NK) cell involved in their
killing of cancer cells. Manipulating this proteolytic process may
provide novel therapies for cancer and diseases resulting from excessive
inflammation.
Interested applicants should email their CV and a cover letter with statement of research interests to: walch003@umn.edu
